Akebia sues CMS for denying coverage for Auryxia under Medicare Part D Becker Hospital Review (Maia Anderson): Akebia believes its drug was denied coverage because CMS officials consider it a mineral, which Medicare typically doesn't cover. Akebia says its treatment is a "synthetic, highly processed compound with a unique structure and novel pharmacologic properties," so it should not be denied, according to STAT.
Wed, 23 Oct 2019 17:36:34 GMT Taking antihypertensives at bedtimes lowers cardiovascular risk. European Heart Journal (Hermida RC): Conclusion -- Routine ingestion by hypertensive patients of ≥1 prescribed BP-lowering medications at bedtime, as opposed to upon waking, results in improved ABP control (significantly enhanced decrease in asleep BP and increased sleep-time relative BP decline, i.e. BP dipping) and, most importantly, markedly diminished occurrence of major CVD events.
Wed, 23 Oct 2019 06:51:29 GMT ISHD Hemodialysis University on September 22-23, in Chicago The International Society for Hemodialysis (ISHD) in collaboration with Indiana University is hosting the 2019 Hemodialysis University (HDU) – From the Unit to the Home. HDU2019 will be held September 22-23, 2019 at the Hilton Rosemont/Chicago O’Hare. (Visit http://www.ishd.org for full details and program schedule)
The ISHD is a society dedicated to education and training in the field of hemodialysis, with a special emphasis on home hemodialysis. This year, we are working with Indiana University to incorporate their annual Home Dialysis Symposium, offering a Home Dialysis Track along with a Hemodialysis Track. Registrants can pick and choose which sessions within the two tracks they would like to attend over the two-day event. The HDU program is meant to help dialysis providers, including nephrologists, nurse practitioners, and nephrology nurses, deal with problems commonly encountered in their patients.
This year’s hemodialysis track addresses a variety of important clinical issues, including volume control, phosphorous binders, blood pressure control, immunosuppressive therapy in dialysis patients, anticoagulants, expanded range hemodialysis, anemia, Management of diabetes in CKD/ESKD and many other topics.
This year’s home dialysis track includes presentations on current home hemodialysis technology, patient selection, patient training, vascular access in home hemo, transitional care units, afternoon demonstrations and a special session on the Advancing Kidney Health Initiative. Rob Blaser with the Renal Physicians Association will discuss the Washington perspective on the Initiative and Dr. Nupur Gupta, HDU Program Chair, will moderate an exciting panel with Dr. Dinesh Chatoth, Associate Chief Medical Officer with Fresenius Medical Care North America, Dr. Martin Schreiber, Chief Medical Officer, Home Modalities, DaVita Kidney Care and Dr. Brent Miller, Michael A. Kraus Professor of Clinical Medicine, Indiana University School of Medicine focused on Strategic Planning for the Advancing Kidney Health Initiative.
You may register and find more info at the following direct link: http://www.ishd.org/meetings-hdu/hdu-2019/
Thu, 15 Aug 2019 03:33:21 GMT SPRINT substudy shows that intensive BP control lowers rate of white matter brain lesions. NIH: In a nationwide study, researchers used magnetic resonance imaging (MRI) to scan the brains of hundreds of participants in the National Institutes of Health’s Systolic Blood Pressure Intervention Trial (SPRINT) and found that intensively controlling a person’s blood pressure was more effective at slowing the accumulation of white matter lesions than standard treatment of high blood pressure.
Fri, 19 Jul 2019 18:37:13 GMT Trump's advancing kidney care initiative ASN Kidney.org: In the first major transformation in kidney care in almost 50 years, the Trump administration today announced the Advancing the American Kidney Health initiative. The comprehensive kidney health strategy will bring sweeping changes to care for people with kidney diseases, including more choices for dialysis modalities, greater access to transplantation, and concerted support for development of innovative therapies, including artificial kidneys.
Thu, 11 Jul 2019 06:07:44 GMT Predicing serum K from the EKG trace measured by an Apple watch. Endgadget.com: "Eureka! The error rate dropped to 1 percent, and the receiver operating characteristic (ROC) curve, a measure of predictive accuracy where 1.0 is perfect, rose from 0.63 at the time of the scatterplot to 0.86."
Tue, 02 Jul 2019 22:29:09 GMT Low grade E. Coli urinary tract infections picked up by DNA testing of urine. Washington Post: For a small study published in December 2018 in the Journal of Clinical Microbiology, University College London researchers used both the standard urine culture test and a DNA test on 63 people (88 percent of them women, as most UTI patients are female) diagnosed with UTIs based on symptoms and white blood cells in their urine, along with 29 UTI-free controls.
Sat, 06 Apr 2019 16:24:16 GMT Rehydrating with soft drinks after exercise increases AKI injury markers Chapman et al, AJP, March, 2019: "Stage 1 AKI (i.e., increased serum creatinine ≥0.30 mg/dl) was detected at postexercise in 75% of participants in the Soft Drink trial compared with 8% in Water trial (P = 0.02). Furthermore, urinary neutrophil gelatinase-associated lipocalin (NGAL), a biomarker of AKI, was higher during an overnight collection period after the Soft Drink trial compared with Water in both absolute concentration [6 (4) ng/dl vs. 5 (4) ng/dl, P < 0.04] and after correcting for urine flow rate [6 (7) (ng/dl)/(ml/min) vs. 4 (4) (ng/dl)/(ml/min), P = 0.03]." Possible mechanism implicated was fructose-mediated release of vasopressin. Of relevance to MesoAmerican nephropathy.
Thu, 28 Feb 2019 12:00:00 GMT CKD Progression Tied to Low Potassium Excretion In a study of patients with chronic kidney disease (CKD), those in the lowest vs highest quartile of 24-hour urinary potassium excretion had a 3-fold increased risk of CKD progression.
Wed, 27 Feb 2019 12:00:00 GMT Kidney Stones Predict Osteoporotic Fracture in CKD In a new study of patients with chronic kidney disease, the presence of kidney stones, compared with their absence, was significantly associated with a 2.3-fold increased risk of osteoporotic fracture.